~ Vitamin E Inhibits Breast Cancer Cell Growth

In a report published in volume 52, issue 1 2005 of the journal Nutrition and Cancer (http://www.leaonline.com /loi/nc) researchers at the University of California Los Angeles showed that adding vitamin E to different breast cancer cell lines helps suppress cell proliferation in response to estrogen.

The researchers tested alpha-tocopherol on two estrogen-receptor positive breast cancer cell lines and on two lines that were estrogen-receptor negative. They found that the vitamin inhibited cell growth dose-dependently in all lines, but while the maximum inhibition in the two estrogen-receptor positive lines was 53 and 75 percent, vitamin E inhibited cell growth by just 14 and 8 percent in the estrogen-receptor negative lines.

To determine if the effect observed in the first two lines was due to a change in estrogen response, they tested the effect of several concentrations of vitamin E in response to varying concentrations of estrogen in the estrogen-receptor positive lines. They found that the growth stimulation induced by the highest concentration of estrogen was decreased in one of the cell lines by 69 percent and in the other by 84 percent by the most potent concentration of vitamin E. When the estrogen responsive cells were grown in an estrogen-deprived medium, vitamin E failed to inhibit cell growth.

The authors remarked that their study is one of the first to report vitamin E's effect on breast cancer cell estrogen response. They note that vitamin E has been shown to diminish breast tenderness and breast cyst size in up to 90 percent of women with benign proliferative breast disease, and as breast tissue hyperplasia is a risk factor for breast cancer, reducing the condition might help prevent cancer. They write, "Vitamin E may be a new nonsteroidal environmental antiestogren, and a dietary supplementation of vitamin E may be a preventive measure for breast cancer."
Related Products and Information


Free Shipping in the Continental U.S. on Orders over $50
The statements made here have not been evaluated by the FDA. The foregoing statements are based upon sound and reliable studies, and are meant for informational purposes. Consult with your medical practitioner to determine the underlying cause of your symptoms. Please always check your purchase for possible allergins and correct dosage on the bottle before use.

While we work to ensure that product information is correct, on occasion manufacturers may alter their ingredient lists. Actual product packaging and materials may contain more and/or different information than that shown on our Web site. We recommend that you do not solely rely on the information presented and that you always read labels, warnings, and directions before using or consuming a product. For additional information about a product, please contact the manufacturer. Content on this site is for reference purposes and is not intended to substitute for advice given by a physician, pharmacist, or other licensed health-care professional. You should not use this information as self-diagnosis or for treating a health problem or disease. Contact your health-care provider immediately if you suspect that you have a medical problem. Information and statements regarding dietary supplements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent any disease or health condition. Life Ex Online assumes no liability for inaccuracies or misstatements about products.