~ Very Berry - and Grape too! Benefits Abound: An Update on Blueberries, Bilberry Extract, Cranberry Extract, and Grape Seed Extract - References
Agarwal C et al. Anticarcinogenic effect of a polyphenolic fraction isolated from grape seeds in human prostate carcinoma DU145 cells: modulation of mitogenic signaling and cell-cycle regulators and induction of G1 arrest and apoptosis. Mol Carcinog 2000; 28:129-38.
Andriambeloson E et at. Natural dietary polyphenolic compounds cause endothelium-dependent vasorelaxation in rat thoracic aorta. J Nutr 1998;128: 2324-33.
Arteel GE et al. Reactions of peroxynitrite with cocoa procyanidin oligomers. J Nutr 2000; 130 (8S Suppl): 2100S-4S.
Asgary S et al. Antioxidant effect of flavonoids on hemoglobin glycosylation. Pharma Acta Helv 1999; 73:223-6.
Atkins, R. The Vita-Nutrient Solution. Simon and Schuster, 1999, pp. 310-311.
Bagchi D et al. Free radicals and grape seed proanthocyanidin extract: importance in human health and disease prevention. Toxicology 2000; 148:187-97.
Baker ME. Flavonoids as hormones. A perspective from an analysis of molecular fossils. Adv Exp Med Biol 1998;439:249-67.
Bomser J et al. In vitro anticancer activity of fruit extracts from Vaccinium species. Planta Med 1996; 62:212-6.
Canali R et al. Reduction of oxidative stress and cytokine-induced neutrophil chemoattractant expression by red wine polyphenols in zinc deficiency induced intestinal damage in rat. Free Radic Biol Med 2000; 28:1661-70.
Cao G et al. Hyperoxia-induced changes in antioxidant capacity and the effect of dietary antioxidants. J Appl Physiol 1999; 86:1917-22.
Cignarella A et al. Novel lipid-lowering properties of Vaccinium myrtillus leaves, a traditional antidiabetic treatment, in several models of rat dyslipidaemia: a comparison with ciprofibrate. Thromb Res 1996; 84:311-22.
Chung KT et al. Tannins and human health: a review. Crit Rev Food Sci Nutr 1998; 38:421-64.
Da Luz PL et al. The effect of red wine on experimental atherosclerosis: lipid-independent protection. Exp Mol Pathol 1999; 65:150-59.
Delmas D et al. Inhibitory effect of reveratrol on the proliferation of human and rat hepatic derived cell lines. Oncol Rep 2000; 7:847-52.
Demrow HS et al. Administration of wine and grape juice inhibits in vivo platelet activity and thrombosis in stenosed canine coronary arteries. Circulation 1995; 91:1182-88.
Ferrandiz ML, Alcaraz MJ. Anti-inflammatory activity and inhibition of arachidonic acid metabolism by flavonoids. Agents Actions 1991; 32:283-88.
Foo LY et al. The structure of cranberry proanthocyanidins which inhibit adherence to uropathogenic P-fimbriated E. coli in vitro. Phytochemistry 2000; 54: 173-81.
Furumoto K et al. Age-dependent telomere shortening is slowed down by enrichement of introcellular vitamin C via suppression of oxidative stress. Life Sci 1998; 63:935-48.
Howell A et al. Inhibition of the adherence of P-fimbriated Escherichia coli to uroepithelial cell surfaces by proanthocyanidin extracts from cranberries. N Engl J Med 1998; 339:1085-6.
Hung LM et al. Cardioprotective effect of resveratrol, a natural antioxidant derived from grapes. Cardiovasc Res 2000; 47:549-55.
Iijima K et al. Red wine polyphenols inhibit proliferation of vascular smooth muscle cells and downregulate expression of cyclin A gene. Circulation 2000; 101:805-11.
Khanduja KL et al. Prevention of N-nitrosodiethylamine-induced lung tumorigenesis by ellagic acid and quercetin in mice. Food Chem Toxicol 1999; 37:313-8.
King A, Young G. Characteristics and occurrence of phenolic phytochemicals. J Am Diet Assoc 1999; 99:213-8.
Koga T et al. Increase of antioxidant potential of rat plasma by oral administration of proanthocyanidin-rich extract from grape seeds. J Agric Food Chem 1999;47: 1892-97.
Leonardi M. [Treatment of fibrocystic disease of the breast with myrtillus anthocyanins. Our experience.] Minerva Ginecol 1993; 45:617-21.
Lin JK, Tsai SH. Chemoprevention of cancer and cardiovascular disease by resveratrol. Proc Natural Sci Counc Repub China B 1999; 23:99-106.
Manna SK et al. Resveratrol suppresses TNF-induced activation of nuclear transcription factors NF-kappaB, activator protein-1 and apoptosis: potential role of oxygen intermediates and lipid peroxidation. J Immunol 2000;164:6509-19.
Man-Ying Chan M et al. Synergy between ethanol and grape polyphenols, quercetin and resveratrol, in the inhibition of the inducible nitric oxide synthase pathway. Biochem Pharmacol 2000; 60:1539-48.
Mian E et al. Anthocyanosides and the walls of the microvessels: further aspects of the mechanism of action of their protective effect in syndromes due to abnormal capillary fragility. Minerva Med 1977; 68:3565-81.
Mitchell SH et al. Resveratrol inhibits the expression and function of the androgen receptor in LNCaP prostate cancer cells. Cancer Res 1999; 59:5892-95.
Mizutani K et al. Resveratrol inhibits AGEs-induced proliferation and collagen synthesis activity in vascular smooth muscle cells from stroke-prone spontaneously hypertensive rats. Biochem Biophys Res Commun 2000; 274:61-67.
Nagata H et al. Antioxidant action of flavonoids, quercetin and catechin, mediated by the activation of glutathione peroxidase. Tokai J Exp Clin Med 1999; 24:1-11.
Narayanan BA et al. P53/p21 expression and its possible role in G1 arrest and apoptosis in ellagic acid treated cancer cells. Cancer Lett 1999; 136:215-21.
Packer L and Colman C. The Antioxidant Miracle. John Wiley and Sons, 1999.
Packer L et al. Antioxidant activity and biologic properties of a procyanidin-rich extract from pine bark, pycnogenol. Free Radic Biol Med 1999; 27:704-24.
Pignatelli P et al. The flavonoids quercetin and catechin synergistically inhibit platelet function by antagonizing the intracellular production of hydrogen peroxide. Am J Clin Nutr 2000; 72:1150-55.
Sakagami H et al. Prevention of oral diseases by polyphenols. In Vivo 1999; 13:155-7.
Sato M et al. Cardioprotective effects of grape seed proanthocyanidins against ischemic reperfusion injurty. J Mol Cell Cardiol 1999; 31:1289-97.
Schneider R et al. Anti-proliferative effects of resveratrol on human colonic cancer cells. Cancer Lett 2000; 158:85-91.
Stein JH. Purple grape juice improves endothelial function and reduces the susceptibility of LDL cholesterol to oxidation in patients with coronary artery disease. Circulation 1999; 100:1050-55.
Szende B. Dose-dependent effect of resveratrol on proliferation and apoptosis in endothelial and tumor cell cultures. Exp Mol Med 2000; 32:88-92.
Takahashi T et al. Procyanidin oligomers selectively and intensively promote proliferation of mouse hair epithelial cells in vitro and activate hair follicle growth in vivo. J Invest Dermatol 1999; 112:310-16.
Thompson, LU et al. Relationship between polyphenol intake and blood glucose resonse of normal and diabetic individuals. Am J Nutr 1984;39:745-51.
Virgili F. Procyanidins extracted from Pinus maritima (Pycnogenol): scavengers of free radical species and modulators of nitrogen monoxide metabolism in activated murine RAW 264.7 macrophages. Free Radic Biol Medicine 1998; 24:1120-29.
Winter JC. The effects of an extract of ginkgo biloba on cognitive behavior and longevity in the rat. Physiol Behav 1998; 63:425-33.
Yamakoshi J et al. Proanthocyanidin-rich extract from grape seeds atttenuates the development of aortic atherosclerosis in cholesterol-fed rabbits. Atherosclerosis 1999; 142:139-49.
Youdim KA et al. Incorporation of the elderberry anthocyanins by endothelial cells increases protection against oxidative stress. Free Radic Biol Medicine 2000; 29:51-60.
Youdim KA, Shukitt-Hale B et al. Polyphenolics enhance red blood cell resistance to oxidative stress in vitro and in vivo. Biochim Biophys Acta 2000; 1523:117-22.
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