References
1. Knight JA. Free radicals: their history and current status in aging and disease. Ann Clin Lab Sci. 1998 Nov-Dec; 28(6):331-46.
2. Reedy EA. The discovery of retrolental fibroplasia and the role of oxygen: a historical review, 1942-1956. Neonatal Netw. 2004 Mar;23(2):31-8.
3. Huang H, Manton KG. The role of oxidative damage in mitochondria during aging: a review. Front Biosci. 2004 May 1;91100-17.
4. Inoue M, Sato EF, Nishikawa M, et al. Mitochondrial generation of reactive oxygen species and its role in aerobic life. Curr Med Chem. 2003 Dec;10(23):2495-505.
5. Ahsan H, Ali A, Ali R. Oxygen free radicals and systemic autoimmunity. Clin Exp Immunol. 2003 Mar;131(3):398-404.
6. Allen RG, Tresini M. Oxidative stress and gene regulation. Free Radic Biol Med. 2000 Feb 1;28(3):463-99.
7. Kashiwagi K, Shinkai T, Kajii E, Kashiwagi A. The effects of reactive oxygen species on amphibian aging. Comp Biochem Physiol C Toxicol Pharmacol. 2005 Feb;140(2):197-205.
8. Lishnevskaia VL. The role of free radicals oxidation in the deterioration of haemovascular homeostasis in aging. Adv Gerontol. 2004;13:52-7.
9. Karatas F, Ozates I, Canatan H, et al. Antioxidant status & lipid peroxidation in patients with rheumatoid arthritis. Indian J Med Res. 2003 Oct;118:178-81.
10. Mazzetti I, Grigolo B, Pulsatelli L, et al. Differential roles of nitric oxide and oxygen radicals in chondrocytes affected by osteoarthritis and rheumatoid arthritis. Clin Sci (Lond). 2001 Dec;101(6):593-9.
11. Bagis S, Tamer L, Sahin G, et al. Free radicals and antioxidants in primary fibromyalgia: an oxidative stress disorder? Rheumatol Int. 2005 Apr;25(3):188-90.
12.Abou-Seif MA, Youssef AA. Evaluation of some biochemical changes in diabetic patients. Clin Chim Acta. 2004 Aug 16;346(2):161-70.
13. Cai Q, Shu XO, Wen W, et al. Genetic polymorphism in the manganese superoxide dismutase gene, antioxidant intake, and breast cancer risk: results from the Shanghai Breast Cancer Study. Breast Cancer Res. 2004;6(6):R647-R55.
14. Ough M, Lewis A, Zhang Y, et al. Inhibition of cell growth by overexpression of manganese superoxide dismutase (MnSOD) in human pancreatic carcinoma. Free Radic Res. 2004 Nov;38(11):1223-33.
15. Manju V, Balasubramanian V, Nalini N. Oxidative stress and tumor markers in cervical cancer patients. J Biochem Mol Biol Biophys. 2002 Dec;6(6):387-90.
16. Lund-Olesen K. Etiology of multiple sclerosis: role of superoxide dismutase. Med Hypotheses. 2000 Feb;54(2):321-2.
17. Choi J, Rees HD, Weintraub ST, et al. Oxidative modifications and aggregation of Cu,Zn-superoxide dismutase associated with Alzheimer and Parkinson diseases. J Biol Chem. 2005 Mar 25;280(12):11648-55.
18. Hattori N. Etiology and pathogenesis of Parkinson's disease: from mitochondrial dysfunctions to familial Parkinson's disease. Rinsho Shinkeigaku. 2004 Apr;44(4-5):241-62.
19. Ueda K, Ogata M. Levels of erythrocyte superoxide dismutase activity in Japanese people. Acta Med Okayama. 1978 Dec;32(6):393-7.
20. Cutler RG. Antioxidants and longevity of mammalian species. Basic Life Sci. 1985;35:15-73.
21. Cutler RG. Antioxidants and aging. Am J Clin Nutr. 1991 Jan;53(1 Suppl):373S-9S.
22. Life Extension-sponsored study #1. Changes in serum levels of superoxide dismutase and catalase in humans after dietary SODzyme™ supplementation.
23. Bauerova K, Bezek A. Role of reactive oxygen and nitrogen species in etiopathologenesis of rheumatoid arthritis. Gen Physiol Biophys. 1999 Oct;18 Spec No:15-20.
24. Hadjigogos K. The role of free radicals in the pathogenesis of rheumatoid arthritis. Panminerva Med. 2003 Mar;45(1):7-13.
25. Life Extension-sponsored study #2. Effects of oral SODzyme™ administration on pain scores in human subjects with arthritis.
26. Bijlsma JW, van de Putte LB. Non-steroidal anti-inflammatory agents (NSAID's) with lesser side effects by selective inhibition of cyclo-oxygenase-2. Ned Tijdschr Geneeskd. 1998 Aug 1;142(31):1762-5.
27. Bjarnason I, Zanelli G, Smith T, et al. The pathogenesis and consequence of non-steroidal anti-inflammatory drug induced small intestinal inflammation in man. Scand J Rheumatol Suppl. 1987;64:55-62.
28. Lazzaroni M, Bianchi PG. Gastrointestinal side effects of traditional non-steroidal anti-inflammatory drugs and new formulations. Aliment Pharmacol Ther. 2004 Jul;20 Suppl 248-58.
29. Beaugerie L, Thiefin G. Gastrointestinal complications related to NSAIDs. Gastroenterol Clin Biol. 2004 Apr;28 Spec No 3C62-C72.
30. Rudic RD, Brinster D, Cheng Y, et al. COX-2 derived prostacyclin modulates vascular remodeling. Circ Res. 2005 May 19.
31. Evensen S, Spigset O, Slordal L. COX-2 inhibitors—one step forward and two steps back. Tidsskr Nor Laegeforen. 2005 Apr 7;125(7):875-8.
32. Meier P, Meyer zu SA, Burnier M. Selective COX-2 inhibitors and cardiovascular risk. Rev Med Suisse. 2005 Feb 23;1(8):543-50.
33. Vouldoukis I, Conti M, Krauss P, et al. Supplementation with gliadin-combined plant superoxide dismutase extract promotes antioxidant defences and protects against oxidative stress. Phytother Res. 2004 Dec;18(12):957-62.
34. Vouldoukis I, Lacan D, Kamate C, et al. Antioxidant and anti-inflammatory properties of a Cucumis melo LC. extract rich in superoxide dismutase activity. J Ethnopharmacol. 2004 Sep;94(1):67-75.
35. Flohe L. Superoxide dismutase for therapeutic use: clinical experience, dead ends and hopes. Mol Cell Biochem. 1988 Dec;84(2):123-31.
36. Muth CM, Glenz Y, Klaus M, et al. Influence of an orally effective SOD on hyperbaric oxygen-related cell damage. Free Radic Res. 2004 Sep;38(9):927-32.
37. Dolegowska B, Chlubek D. Isoprostanes—new possibility of the oxidative stress estimation. Przegl Lek. 2004;61(12):1410-4.
38.Caruso C, Lio D, Cavallone L, Francheschi C. Aging, longevity, inflammation, and cancer. Ann NY Acad Sci. 2004 Dec;1028:1-13.
39. Kortekangas P, Peltola O, Toivanen A, Aro HT. Synovial fliud L-lactic acid in acute arthritis of the adult knee joint. Scand J Rheumatol. 1995;24(2):98-101.
40. Kong Y, et al. korea Cancer Center Hospital. (2004) Influence of an orally effective superoxide dismutase (GliSODin®) on strenuous exercise-induced changes of blood antioxidant enzymes and plasma lactate. Poster presentation at the AACC, July 2004.
41. Chenal H, Davit-Spraul A, Legrand J, et al. Restored antioxidant circulating capacities in west African AIDS patients receiving an antioxidant nutraceutical Cucumis melo extract rich in Superoxide dismutase activity (GliSODin®). [Submitted for publication.]