~ September 2009 - CoQ10 - the Energy Supplement

Contents . . .

  • Peggy Fleming: Energized By CoQ10

    By Donna Caruso

    "I won the Olympics when I was a teenager," says 1968 Gold Medalist figure skater Peggy Fleming, "and I skated professionally for many, many years after that. In some ways, it was a difficult time for me. There aren't too many Olympic sports that require you to go out and perform for the next 30 years with people expecting to see Olympic quality performances every time. It's really hard to keep up your health and your craft so you always feel proud of yourself."

    By all accounts, Peggy Fleming is one of the icons of American figure skating; a vision of grace, beauty, athleticism and artistic creativity that has rarely--if ever--been equaled. But while her love of skating led her naturally to a career as a figure skating commentator for ABC Sports, she has had equal success as a health care advocate, an author, a California winery co-owner and most recently, a spokesperson for a coenzyme Q10 supplement company.

    In an exclusive interview with Life Extension® magazine, Fleming talks about her life, her interests, her personal health regimen, and why she is working to create greater awareness of the benefits of CoQ10.

    Read more . . .

  • Beyond Colonoscopy to Real Protection

    By Julius Goepp, MD

    The public has long been led to believe that regular colonoscopy screenings offer virtually foolproof pro-tection from colorectal cancer death--a 90% mortality risk reduction according to established medical consensus. The latest research suggests the truth may be far less reassuring.

    In one of the largest population studies of its kind, involving over 60,000 individuals, colonoscopies failed to detect the majority of cancers on the right side of the colon and nearly one third of cancers on the left side of the colon. This does not mean you should skip regular colonoscopy screening. What it indicates according to the authors of the case-controlled study is that colonoscopies most likely afford only a 60-70% mortality risk reduction.

    Given that colorectal cancer is the second leading cause of cancer death in the United States for both men and women, a renewed focus on prevention will be required to provide adequate protection from colorectal cancer death. The good news is that advances in our understanding of the molecular basis of colon cancer have yielded a broad array of nutrient-based preventive strategies--without the need for toxic, potentially debilitating pharmaceutical interventions.

    Read more . . .

  • Sep 09 CoQ10 and Cancer Treatment

    By William Faloon

    For more than a decade, Life Extension® has reported on small clinical studies that demonstrate beneficial effects in those with certain cancers who supplement with coenzyme Q10.

    More recent studies have not only documented clinical improvements, but also have identified probable mechanisms by which CoQ10 may help slow tumor growth. Some of these mechanisms include immune augmentation, suppression of vascular endothelial growth factor (that facilitates tumor angiogenesis), and reduction of inflammatory markers that may facilitate cancer cell propagation.

    Melanoma and breast cancer are two types of malignancies for which CoQ10 has demonstrated substantial clinical benefit. Regrettably, the media and cancer establishment have ignored these promising discoveries that could save many lives.

    For example, a recent melanoma study compared the effects of administering alpha interferon with or without daily CoQ10 (400 mg). There was an astounding 10-fold lower risk of metastasis in the CoQ10-supplemented group! This effect was even more pronounced for those with more advanced melanoma, where CoQ10-supplemented patients were 13 times less likely to develop metastasis. Alpha interferon is an immune boosting drug that can induce side effects so severe that patients have to discontinue it. In this study,2 only 22% of CoQ10-supplemented patients developed side effects compared to 82% not taking supplemental CoQ10.

    Our editorials have harshly criticized the National Cancer Institute for failing to fund larger studies in order to ascertain exactly how effective CoQ10 may be as an adjuvant cancer therapy.

    It is our pleasure to reprint an update by the National Cancer Institute that presents their views on the role that CoQ10 may play in cancer treatment. Considering that this report emanates out of a federal agency that is normally biased against alternative therapies, we are quite pleased with the relative balance this report provides.

    We do take issue with the National Cancer Institute's insinuation of CoQ10 side effects, as these are likely the result of the underlying cancer and/or problems inflicted by toxic chemo drugs. Of the tens of thousands of healthy Life Extension® members who use CoQ10, none report these side effects.

    Read more . . .

  • Featured Product: COQ10 - Super BioActive CoQ10 Ubiquinol Softgels

    When it comes to achieving optimal results from your CoQ10 supplement, how much you absorb is of critical importance. Since 1983, Life Extension has continuously sought out the purest, most bioavailable CoQ10 available. Now, Japan's largest CoQ10 producer has patented a form of CoQ10 that offers unprecedented bioavailability--capable of increasing human blood levels up to 8 times more efficiently than the higher-absorption CoQ10 products on the market today.

    In studies from Japan, this superior new form of CoQ10 has shown remarkable antiaging effects. In one study, it was 40 percent more effective than conventional CoQ10 in slowing markers of aging in middle-aged mice. In a study of aged rats, this new form of CoQ10 demonstrated anti-fatigue effects that were 2.5 times greater than conventional CoQ10 supplements.

    The reason this new form of CoQ10 is so effective is that scientists have succeeded for the first time in producing a stabilized ubiquinol capsule form of CoQ10. While CoQ10 exists in both ubiquinol and ubiquinone forms, the ubiquinol form has been shown to be vastly more bioavailable than conventional ubiquinone CoQ10. In a study measuring absorption in humans supplementing with 150mg and 300mg , far lower doses of ubiquinol CoQ10 produced blood plasma levels of CoQ10 that were equivalent to those produced by much higher doses of ubiquinone. In fact, it would take up to 8 times more ubiquinone than ubiquinol to raise CoQ10 blood levels to the same level.

    With its superior absorption and ability to remain bioavailable over much longer periods of time, most healthy people will need to take just one capsule twice daily to obtain significantly higher blood levels of CoQ10.

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