~ November 2004 - Holiday Specials: Deep Discounts, Recipes and More!

Contents . . .
  • Recipes for Healthy, Happy Holidays

    Complement Your Traditional Holiday Meal with These Delicious Side Dishes

    Diet is always your first line of defense in staying healthy and enjoying life. Kale and other dark green leafy vegetables contain vitamins and minerals that support bone health, such as calcium, magnesium, and vitamin K.

    Try adding one of these delicious side dishes to your holiday menu.

    Kale with Root Vegetables Saute - Kale, parsnip, turnip, red potatoes, onion, and garlic.
    Get the recipe . . .

    Baked Sage and Kale Conrbread Dressing - Kale, celery, onion, fresh sage, black pepper cornbread, croutons, and broth.
    Get the recipe . . .

    Braised Kale Crostini - Kale, Italian bread, olive oil, garlic, red pepper, and broth.
    Get the recipe . . .
  • Top Bone Health Supplements - Bone loss is by far easier to prevent than to reverse. Start your prevention program with these important supplements.

    Bone Assure - Calcium is the mineral that automatically comes to mind when considering bone health. However, other minerals are equally important in the treatment and prevention of osteoporosis, such as zinc, magnesium, and boron. Bone Assure contains all of these and more, in a balanced formula maximized for optimal absorption, and is an excellent value at a very reasonable price.

    Vitamin K (K1 and K2) - Most osteoporosis studies are done on postmenopausal women, and vitamin K shows remarkable results against bone loss in this population. In a study from The Netherlands, 1mg of vitamin K a day for 2 weeks increased a bone building protein gamma-carboxyglutamic acid (Gla) in postmenopausal women, helping to elevate it. Another study shows that vitamin K slows calcium loss by one-third in people who have a tendency to lose it. If you are taking a blood thinner, you should not take Vitamin K without first consulting your doctor. Nevertheless, Vitamin K is very promising for those who can take it.

    Ipriflavone - Early reports on ipriflavone were positive for the prevention of bone loss. Gennari et al. (1998) studied whether ipriflavone could prevent bone loss occurring shortly after menopause. In the study, 56 women with low vertebral bone density and postmenopausal symptoms for less than 5 years were randomly selected to receive either ipriflavone or placebo. All subjects received 1000mg of elemental calcium daily. After 2 years, vertebral density declined in the women taking only calcium, but did not change in those receiving ipriflavone. Research also suggests that long-term treatment with ipriflavone may be considered safe and may increase bone density - and possibly prevent fractures - in elderly patients with established osteoporosis.

    Magnesium - Many people in North America who consume an average diet have magnesium deficiency, and magnesium is important in bone structure. Magnesium deficiency comes about because most magnesium in our diet comes from the magnesium contained in the chlorophyll molecule found mainly in dark green leafy vegetables--not something that most people eat on a daily basis. Some researchers are now also reporting that magnesium deficiency plays a significant role in the development of osteoporosis. Studies have shown that women with osteoporosis tend to have a lower magnesium intake than normal and lower levels of magnesium in their bones. A magnesium deficiency can also affect the production of the biologically active form of vitamin D, thereby further promoting osteoporosis.

    DHEA and Melatonin - Hormones play a critical role in maintaining bone mass. Bone health is NOT for women only! (See The Hidden Dangers of Male Osteoporosis) In men, attention to testosterone level is especially important. DHEA and melatonin may be helpful in regulating hormones in men. In some cases consideration for the use of some progesterone should be made. Supplemental DHEA is contraindicated in both men and women with certain hormone-related cancers, but is generally worth looking into. (Refer to the DHEA Replacement Therapy protocol and Male Hormone Modulation Therapy protocol for more information).
  • Featured Product - Bone Assure - Bone Assure is a comprehensive formula that can help maintain bone mineral density by:

    • Sustaining bone mineral mass by providing a potent amount of elemental magnesium and a highly absorbable form of calcium (bisglycinate) that has been shown to assimilate 1.8 times better than calcium citrate.

    • Maintaining the organic bone matrix with the minerals zinc, manganese, silica, and copper that are required for the formation of collagen and other living connective tissues. Manganese has been shown to specifically act as an anabolic catalyst in the development and maintenance of the organic bone matrix.

    • Facilitating the absorption of calcium into the bloodstream by providing vitamin D3. Once in the bloodstream, vitamin D3 then acts as a hormone to direct calcium into the bone matrix.

    • Preventing excessive urinary excretion of calcium and magnesium by providing the trace mineral boron.

    • Lowering elevated homocysteine levels that have been shown to damage the organic bone matrix, by providing small amounts of folic acid, B6 and TMG.


    Commercial calcium supplements provide only limited protection against the demineralization of bone that occurs with aging. The scientific literature, on the other hand, documents a wide range of minerals that are vital to maintaining strong, healthy bones. For those who have already lost bone density, the proper combination of nutrients can help restore bone mass by rebuilding the organic matrix that holds minerals such as calcium in place.
  • Protocol: Prevention - Osteoporosis is a major public health issue for more than 28 million Americans, 80% of whom are women. It is estimated that in the United States today, 10 million individuals already have osteoporosis, and 18 million more probably have a low bone density, placing them at increased risk for osteoporosis in later years.

    Although osteoporosis is often thought of as an old person's disease, it can affect younger people who have hormonal difficulties, particularly women with anorexia, bleeding, or menstrual abnormalities in their 20s.

    Osteoporosis also occurs in men. Osteoporosis is responsible for more than 1.5 million fractures annually, including 300,000 hip fractures, 700,000 vertebral fractures, and 250,000 wrist fractures.

    Bone is composed of 30% organic and 70% mineral substances. The organic portion is called osteoid and acts as the matrix or framework for the mineral part. Osteoid is produced by bone cells called osteoblasts. The mineral part consists of calcium and other valuable minerals and hardens upon the osteoid matrix. Osteoclasts are large bones which reshape mature bone by resorbing the mineral and organic components. Bone formation and resorption are normal, continuous processes.

    In osteoporosis, there is an overall decrease in bone mass because resorption by osteoclasts exceeds bone formation. Osteoblasts continue to produce bone, but not to the same extent that it is being resorbed.

    During the last two decades, a number of valuable treatments for osteoporosis have become available and are reviewed in this protocol.

    The most significant treatment is still prevention of bone loss, particularly for postmenopausal women. Primary prevention, before there is any actual bone loss, can probably be accomplished at first with only diet, supplementation, and exercise changes.

    Secondary prevention, when there has been some loss but the goal is to prevent further reduction or to increase bone density, will most likely require hormonal replacement therapy. Much of this is discussed in the Female Hormone Replacement Therapy protocol, particularly with regard to progesterone and estrogen and to concerns about estrogen side effects.
    (http://www.lifeextensionvitamins.com/fehoreth.html)

    The following nutrients, hormones, and drugs should be considered in the prevention and treatment of osteoporosis:

    1. Proper nutritional supplementation with vitamins and minerals, in particular calcium. Six capsules a day of Bone Assure provide the ideal dosages and forms of calcium, magnesium, zinc, manganese, and vitamin D3, boron and other nutrients to protect bone density.

    2. Weight-bearing exercise may help increase bone density.

    3. Supplemental hormones such as DHEA, 25-50mg a day and melatonin, 300mcg - 3mg each night should be considered by both men and women.

    4. Vitamin K in the dose of 10mg a day facilitates the formation of a bone-building protein and dramatically reduces fracture risk. Do not take vitamin K if you are taking Coumadin or some other type of anticoagulant medication. For treatment, take up to 45mg a day under the supervision of a physician who monitors blood coagulation factors.

    5. Soy extract may improve bone density and bone mineral content, 55-110 mg of active isoflavones (genistein, daidzen, and glycitein) each day.

    6. Consider bisphosphonate drug therapy if there is any evidence of a loss of bone mineral density as measured by a QCT test.

    7. Application of natural progesterone cream may stabilize or improve bone density.

    8. Men should pay particular attention to testosterone replacement therapy (refer to the Male Hormone Modulation protocol for details).

    9. Ipriflavone may suppress bone resorption, 300mg a day.

    10. Avoid red meat and switch to fish as a protein alternative. Using a supplement called Super GLA/DHA (provides gamma linolenic acid from borage oil and DHA from fish oil) is the best documented way of suppressing excess levels of pro-inflammatory cytokines, such as interleukin-6 (IL-6) that break down bone.

    11. Refer to the Female Hormone Replacement Therapy protocol for additional information regarding estrogen and progesterone therapy.

    Read the full protocol . . .
To see a list of all supplements, please check our Index or use our Search feature.

If you have any questions, please contact us at info@lifeextensionvitamins.com, 1-510-527-3005 or 1-888-771-3905.


Free Shipping in the Continental U.S. on Orders over $50
The statements made here have not been evaluated by the FDA. The foregoing statements are based upon sound and reliable studies, and are meant for informational purposes. Consult with your medical practitioner to determine the underlying cause of your symptoms. Please always check your purchase for possible allergins and correct dosage on the bottle before use.

While we work to ensure that product information is correct, on occasion manufacturers may alter their ingredient lists. Actual product packaging and materials may contain more and/or different information than that shown on our Web site. We recommend that you do not solely rely on the information presented and that you always read labels, warnings, and directions before using or consuming a product. For additional information about a product, please contact the manufacturer. Content on this site is for reference purposes and is not intended to substitute for advice given by a physician, pharmacist, or other licensed health-care professional. You should not use this information as self-diagnosis or for treating a health problem or disease. Contact your health-care provider immediately if you suspect that you have a medical problem. Information and statements regarding dietary supplements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent any disease or health condition. Life Ex Online assumes no liability for inaccuracies or misstatements about products.