~ New Method to Reduce Lactose Intolerance - References


  1. Obermayer-Pietsch BM, Gugatschka M, Reitter S, et al. Adult-type hypolactasia and calcium availability: decreased calcium intake or impaired calcium absorption? Osteoporos Int. 2007 Apr;18(4):445-51. Epub 2006 Nov 14.
  2. Savaiano D. Lactose intolerance: an unnecessary risk for low bone density. Nestle Nutr Workshop Ser Pediatr Program. 2011;67:161-71.
  3. Fraissl L, Leitner R, Missbichler A. Novel formulation of neutral lactase improves digestion of dairy products in case of lactose intolerance. Clinical and Translational Allergy. 2011 August 12;1(Suppl 1):104.
  4. SCIOTEC Diagnostic Technologies GmbH. Scientific Information on lactose intolerance and Lactosolv Tulln an der Donau, Austria 2012.
  5. Bayless TM, Rothfeld B, Massa C, Wise L, Paige D, Bedine MS. Lactose and milk intolerance: clinical implications. N Engl J Med. 1975 May 29;292(22):1156-9.
  6. Available at: http://emedicine.medscape.com/article/187249-overview#showall. Accessed June 18, 2012.
  7. Beja-Pereira A, Luikart G, England PR, et al. Gene-culture coevolution between cattle milk protein genes and human lactase genes. Nat Genet. 2003 Dec;35(4):311-3.
  8. Di Stefano M, Veneto G, Malservisi S, et al. Lactose malabsorption and intolerance and peak bone mass. Gastroenterology. 2002 Jun;122(7):1793-9.
  9. Kudlacek S, Freudenthaler O, Weissboeck H, Schneider B, Willvonseder R. Lactose intolerance: a risk factor for reduced bone mineral density and vertebral fractures? J Gastroenterol. 2002;37(12):1014-9.
  10. Lomer MC, Parkes GC, Sanderson JD. Review article: lactose intolerance in clinical practice--myths and realities. Aliment Pharmacol Ther. 2008 Jan 15;27(2):93-103.
  11. Suarez FL, Savaiano DA, Levitt MD. A comparison of symptoms after the consumption of milk or lactose-hydrolyzed milk by people with self-reported severe lactose intolerance. N Engl J Med. 1995 Jul 6;333(1):1-4.
  12. Sieber R, Stransky M, de Vrese M. Lactose intolerance and consumption of milk and milk products. Z Ernahrungswiss. 1997 Dec;36(4):375-93.
  13. Montalto M, Curigliano V, Santoro L, et al. Management and treatment of lactose malabsorption. World J Gastroenterol. 2006 Jan 14;12(2):187-91.
  14. Vonk RJ, Priebe MG, Koetse HA, et al. Lactose intolerance: analysis of underlying factors. Eur J Clin Invest. 2003 Jan;33(1):70-5.
  15. Beyerlein L, Pohl D, Delco F, Stutz B, Fried M, Tutuian R. Correlation between symptoms developed after the oral ingestion of 50 g lactose and results of hydrogen breath testing for lactose intolerance. Aliment Pharmacol Ther. 2008 Apr;27(8):659-65.
  16. Uchida N, Sakamoto O, Irie M, et al. Two novel mutations in the lactase gene in a Japanese infant with congenital lactase deficiency. Tohoku J Exp Med. 2012;227(1):69-72.
  17. Hermans MM, Brummer RJ, Ruijgers AM, Stockbrugger RW. The relationship between lactose tolerance test results and symptoms of lactose intolerance. Am J Gastroenterol. 1997 Jun;92(6):981-4.
  18. Rosado JL, Solomons NW, Lisker R, Bourges H. Enzyme replacement therapy for primary adult lactase deficiency. Effective reduction of lactose malabsorption and milk intolerance by direct addition of beta-galactosidase to milk at mealtime. Gastroenterology. 1984 Nov;87(5):1072-82.
  19. Garcia-Garibay M, Gomez-Ruiz L. Uses of microbial beta-galactosidases to reduce lactose content in milk and dairy products. Rev Invest Clin. 1996 Nov;48 Suppl:51-61.
  20. Tello-Solis SR, Jimenez-Guzman J, Sarabia-Leos C, et al. Determination of the secondary structure of Kluyveromyces lactis beta-galactosidase by circular dichroism and its structure-activity relationship as a function of the pH. J Agric Food Chem. 2005 Dec 28;53(26):10200-4.
  21. Solomons NW, Guerrero AM, Torun B. Effective in vivo hydrolysis of milk lactose by beta-galactosidases in the presence of solid foods. Am J Clin Nutr. 1985 Feb;41(2):222-7.
  22. Montalto M, Nucera G, Santoro L, et al. Effect of exogenous beta-galactosidase in patients with lactose malabsorption and intolerance: a crossover double-blind placebo-controlled study. Eur J Clin Nutr. 2005 Apr;59(4):489-93.
  23. Solomons NW, Guerrero AM, Torun B. Dietary manipulation of postprandial colonic lactose fermentation: II. Addition of exogenous, microbial beta-galactosidases at mealtime. Am J Clin Nutr. 1985 Feb;41(2):209-21.
  24. Coenen TM, Bertens AM, de Hoog SC, Verspeek-Rip CM. Safety evaluation of a lactase enzyme preparation derived from Kluyveromyces lactis. Food Chem Toxicol. 2000 Aug;38(8):671-7.
  25. Pereira-Rodriguez A, Fernandez-Leiro R, Gonzalez-Siso MI, Cerdan ME, Becerra M, Sanz-Aparicio J. Structural basis of specificity in tetrameric Kluyveromyces lactis beta-galactosidase. J Struct Biol. 2012 Feb;177(2):392-401.
  26. Wang Y, Harvey CB, Hollox EJ, et al. The genetically programmed down-regulation of lactase in children. Gastroenterology. 1998 Jun;114(6):1230-6.
  27. Bahna SL. Cow’s milk allergy versus cow milk intolerance. Ann Allergy Asthma Immunol. 2002 Dec;89(6 Suppl 1):56-60.

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