Nattokinase (100mg) - 60 Softgels

Nattokinase (100mg) - 60 Softgels
Item# ARG75370

Allergy Research Group / Nutricology Nattokinase 60 softgels/100mg.ea

Nattokinase is a natural enzyme with anti-clotting properties.

Source: Allergy Research Group/Nutricology

Nattokinase NSK-SD is isolated, purified and encapsulated nattokinase, an enzyme derived from boiled soybeans and Bacillus subtilis natto. Research has shown nattokinase to support healthy coagulation of blood within normal levels and enhance fibrinolytic activity.

We tested recently introduced products and few meet the standards of Dr. Sumi, the discoverer of nattokinase, and Dr. Holsworth, the leading U.S. researcher of nattokinase. We offer only the patented NSK-SD formulation with no Vitamin K2, the only form that has been tested for safety. Each batch is tested to ensure potency.

NSK-SD is a trademark of Japan BioScience Laboratory.

The Possible Benefits of Nattokinase, a Dietary Supplement
  • Has been shown to be nutritionally supportive for maintenance and enhancement of normal healthy endogenous fibrinolysis, the dissolution of the essential portion of the blood clot or thrombus.
  • Nutritional support for healthy blood pressure levels.
Activator (t-PA) and acylated plasminogen-streptokinase activator complex (APSAC) has significant benefits in reducing the morbidity and mortality of some cardiovascular conditions. The benefits of thrombolytic therapy extend far beyond the early survival period well into a decade after the first incidence of cardiovascular ischemia caused by blood clots restricting blood flow.

Although early clinical studies utilized intravascular administration of thrombolytic agents, it is now clear that some agents may be successfully administered orally, encapsulated for delivery into the small intestine. Clinical and animal studies demonstrate that the intestinal absorption of urokinase produces a prolonged level of activity in plasma together with a significant lytic effect on thrombi.

While investigating natural food sources for fibrinolytic activity, a University of Chicago researcher Dr. Hiroyuki Sumi, discovered a potent fibrinolytic enzyme in a popular Japanese fermented food. His research group tested 173 foods including the traditional Japanese food called Natto, made from boiled and fermented soybeans. Natto has been part of the Japanese diet for centuries and the Japanese believed that this food item enhances cardiovascular health.


Nattokinase (NK) is a profibrinolytic serine protease extracted and purified from natto, a traditional fermented soybean food popular in Japan. The fermentation process includes incubating boiled soybeans with Bacillus natto.

Current research suggests that NK may be useful in the maintenance and enhancement of normal healthy endogenous fibrinolysis, the dissolution of the essential portion of the blood clot or thrombus. Maintenance of optimum functioning of the body's fibrinolytic/thrombolytic systems may offer decreased risk of dangerous blood clots that contribute to a variety of conditions involving particularly the brain and cardiovascular systems.

The importance of blood clotting is obvious in relationship to survival in cases of injury. But the increasing stickiness of blood can have consequences. Antioxidants are supportive in protecting prostacyclin, a prostaglandin that thins blood. Antioxidants also scavenge free radicals, which are required to activate the blood clotting effects of thromboxane. These effects are mediated through the blood supply and have themselves full systemic manifestations.

Clinical studies have shown that intravascular thrombolytic therapy with agents such as streptokinase, urokinase, tissue plasminogen contain vitamin K.

Subsequent research has shown that NK is absorbed from the intestinal tract and degrades plasma fibrinogen. As an endogenous plasminogen activator, NK's thrombolytic activity can be maintained for a relatively long time.

In summary, Nattokinase can be a valuable part of a cardiovascular health program that includes prophylactic use of anti-thrombotic agents.

Each 1 softgel contains:

Nattokinase NSK-SD (2000 FU) - 100 mg

Other ingredients: Soybean oil, gelatin, glycerin, soybean lecithin, glycerin fatty acid ester, and beeswax.

Suggested use: As a dietary supplement, 1 softgel two times daily initial dose, or as directed by a healthcare practitioner. May be taken with or without food. Take with 8-10 ounces of water. If taken with anticoagulant drugs, use under medical supervision. Contraindicated in any condition associated with bleeding.

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