~ Melatonin's Effect on Cancer Patients Indicates Improved Survival
First ever meta-analysis of melatonin's effect on cancer patients indicates improved survival.
The results of a meta-analysis of clinical trials examining the effects of melatonin on individuals being treated for cancer were presented at the 20th Annual Meeting of the American Association of Naturopathic Physicians, held August 24 through 26 2005 in Phoenix, Arizona. The report, entitled, "Melatonin in the Treatment of Cancer: A Systematic Review of Randomized Controlled Trials and Meta-Analysis", is currently under peer review by a medical journal.
Melatonin is a hormone manufactured by the pineal gland in the brain that has an effect on the body's wake/sleep cycle. The results of some studies have suggested that melatonin may exert a protective effect against cancer, and that it may also be of benefit during chemotherapy and radiation treatments.
Lead author Leslie Axelrod and her Canadian colleagues searched medical databases for reports that provided the results of randomized controlled trials of melatonin combined with other treatments in cancer patients with solid tumors, including data on one year survival. Ten reports published between 1992 and 2003 that provided information on trials conducted in Italy and Poland met the researchers' criteria. The studies enrolled a combined total of 643 men and women of varying ages.
The researchers found a consistent benefit across all melatonin dosages on one year survival when the hormone was tried as an adjunct therapy in a variety of advanced stage cancers. Compared to those who did not receive the hormone, those who received melatonin had a 44 percent lower risk of death one year following their trial enrollment. Although the meta-analysis had its limitations, the authors concluded that "the substantial reduction in risk of death, low adverse events reported and low costs related to this intervention suggest great potential for melatonin in treating cancer."
Free Shipping in the Continental U.S. on Orders over $50
The statements made here have not been evaluated by the FDA. The foregoing statements are based upon sound and reliable studies, and are meant for informational purposes. Consult with your medical practitioner to determine the underlying cause of your symptoms. Please always check your purchase for possible allergins and correct dosage on the bottle before use.
While we work to ensure that product information is correct, on occasion manufacturers may alter their ingredient lists. Actual product packaging and materials may contain more and/or different information than that shown on our Web site. We recommend that you do not solely rely on the information presented and that you always read labels, warnings, and directions before using or consuming a product. For additional information about a product, please contact the manufacturer. Content on this site is for reference purposes and is not intended to substitute for advice given by a physician, pharmacist, or other licensed health-care professional. You should not use this information as self-diagnosis or for treating a health problem or disease. Contact your health-care provider immediately if you suspect that you have a medical problem. Information and statements regarding dietary supplements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent any disease or health condition. Life Ex Online assumes no liability for inaccuracies or misstatements about products.