~ May 2007 - Cardiovascular Health - A New Approach

Contents . . .
  • Enhancing Cardiac Energy with Ribose

    By Stephen T. Sinatra, MD, and James C. Roberts, MD

    After years of performing angiograms and emergency cardiac procedures, two cardiologists—Drs. Stephen Sinatra and James Roberts—grew weary of seeing their patients fail to achieve lasting cardiovascular health. As they began to integrate complementary therapies such as coenzyme Q10, L-carnitine, and D-ribose into their patient care protocols, they noticed an astonishing result: hospital admissions for their heart patients dropped dramatically.

    In the following excerpt from their new book Reverse Heart Disease Now, these forward-thinking physicians report how they use D-ribose in their practice to help patients suffering from coronary artery disease, congestive heart failure, peripheral arterial disease, and more. Their impressive results may well herald a new era of preventive cardiology that uses integrative approaches to prevent and reverse cardiovascular disease, before catastrophe strikes. D-ribose is the new kid on the heart supplement block. As a building block of ATP (adenosine triphosphate), it rapidly restores depleted energy in sick hearts.

    You probably haven't heard about D-ribose. But you will. It's that good. Every cell in the human body makes some of this simple sugar molecule, but only slowly and to varying degrees, depending on the tissue. The liver, adrenal glands, and fat tissue produce the most—enough to serve their purpose of making compounds involved in the production of hormones and fatty acids. But tissue elsewhere has little.

    Red meat, particularly veal, contains the highest dietary concentration of D-ribose, but not significant enough to provide any meaningful nutritional support, especially to unwell individuals. Heart, skeletal muscle, brain, and nerve tissue can only make enough D-ribose to manage their day-to-day needs when their cells are not stressed. Unfortunately, these cells lack the metabolic machinery to make D-ribose quickly when they come under metabolic stress such as blood and oxygen deprivation (ischemia). When oxygen or blood flow deficits are chronic, as in heart disease, tissues can never make enough D-ribose. Cellular energy levels become depleted.

    Read more . . .
  • Pomegranate: Powerful Protection for Aging Arteries—and Much More

    By Tiesha D. Johnson, BSN, RN

    Every year, more than a million Americans are struck down by a heart attack or stroke. For many, sudden death will be their first—and last—symptom of undetected vascular disease. Those lucky enough to survive often face invasive procedures like angioplasty and coronary bypass surgery, followed by a lifetime of curtailed physical activity and costly heart medications. If you trust your vascular health to mainstream doctors, you may be gambling with your life. Although cardiovascular disease remains the nation's number-one killer, American medicine prioritizes heart disease treatment rather than prevention. Sadly, it has become far more profitable to treat heart disease than to prevent it.

    Fortunately, natural strategies that can help avert life-threatening heart attacks and strokes are readily available today. One of the most promising heart-protective agents to emerge in recent years is pomegranate. Packed with unique antioxidants that guard the body's endothelial cells against free-radical assault, pomegranate has been shown to prevent—and even reverse—cardiovascular disease.

    Research also shows that pomegranate can stop the progression of deadly prostate cancer. And scientists are now exploring pomegranate's potential in averting ailments ranging from diabetes to Alzheimer's disease, as well as its role in supporting skin, joint, dental, and liver health.

    In this article, we examine the growing volume of research that attests to pomegranate's myriad health-promoting properties—particularly its role in safeguarding the delicate endothelial cells that line blood vessels and are so critical to preserving optimal vascular function in aging adults.

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  • Cimetidine: A Common Heartburn Remedy Complements Conventional Cancer Therapy

    By Cynthia Haines, MD

    Conventional cancer therapies do not always eradicate the cancer, leading patients to seek out adjuvant therapies that may confer additional benefits. More than two decades ago, Life Extension called attention to the over-the-counter heartburn drug cimetidine—more commonly known by its brand name, Tagamet—as a complementary cancer treatment. Although cimetidine was developed to relieve heartburn, acid indigestion, and sour stomach, numerous studies demonstrate that this readily available medication may offer powerful support in the fight against cancer.Unfortunately, many cancer patients and even oncologists remain unaware of the compelling evidence demonstrating its efficacy.

    By preventing cancer metastasis (spread), slowing or halting tumor growth, and prolonging survival, cimetidine may serve as an important adjuvant therapy for people fighting colon cancer and other malignancies.

    What Is Cimetidine?

    Cimetidine, or Tagamet, reduces the production of stomach acid by binding with H2 receptors on the acid-secreting cells of the stomach lining. These receptors normally bind with histamine to produce stomach acid, which helps to break down food. By competing with histamine to bind with H2 receptors, cimetidine reduces the stomach's production of acid.

    This mechanism of action accounts for cimetidine's use in managing gastroesophageal reflux disease (GERD), a condition marked by an excess of stomach acid. In fact, its use in treating gastric (stomach) disorders dates back several decades.

    Anti-emetic drugs are used to prevent or treat nausea and vomiting. Before stronger anti-emetic drugs became available, cimetidine was prescribed to treat nausea associated with chemotherapy. As far back as 1988, scientists observed that colon cancer patients who had been treated with cimetidine had a notably better response to cancer therapy than those who did not receive cimetidine.1 Now, nearly 30 years of published research suggests that cimetidine may exert its most profound effects not as a heartburn remedy, but as an anti-cancer drug.

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  • Guarding Against the Dangers of Vitamin D Deficiency

    By Tiesha D. Johnson, BSN, RN

    The long, dark days of another winter have come and gone. Tens of millions of Americans would be surprised to learn that winter has left them deficient in vitamin D. Your chances of being one of them are probably much greater than you imagine.

    Vitamin D is synthesized in the skin in response to sunlight exposure, but few people achieve optimal levels this way, in part due to the limited ultraviolet light available during the winter months. This seasonal deficit is compounded by the fact that many people avoid sun exposure during the spring and summer months because of concern about premature skin aging and cancers like melanoma. Alarming new research suggests that these factors are contributing to a year-round epidemic of vitamin D deficiency, particularly in elderly adults.

    Vitamin D does far more than promote healthy teeth and bones. Its role in supporting immunity, modulating inflammation, and preventing cancer make the consequences of vitamin D deficiency potentially devastating. A growing number of scientists who study vitamin D levels in human populations now recommend annual blood tests to check vitamin D status.

    In this article, we examine the factors that contribute to the widespread prevalence of vitamin D deficiency, the latest studies supporting vitamin D's critical role in preventing disease, and how much supplemental vitamin D you need to achieve optimal blood levels.

    Read more . . .
  • Featured Product: d-Ribose

    People suffering from cardiac and other debilitating health problems often exhibit severely depleted cellular energy in heart and muscle tissue, which can greatly impair normal daily functions.

    The primary source of energy for all cellular processes is a molecule known as ATP (adenosine triphosphate). Healthy, active cells constantly replenish their supply of ATP to produce vital cellular energy. However, under conditions of stress, injury, or aging, critical body tissues such as heart and skeletal muscles cannot produce ATP quickly enough to perform optimally.

    D-ribose, a carbohydrate molecule found in every living organism, facilitates the production of ATP. In studies of healthy athletes as well as those who have suffered injury to the heart muscle, supplying fatigued muscle cells with D-ribose quickly restored ATP levels to normal. By helping to rapidly refill depleted energy stores, D-ribose may be especially beneficial for people coping with cardiac and other problems marked by impaired cellular energy production. D-Ribose Caps and D-Ribose Powder can help speed energy recovery, increase energy reserves, and maintain healthy energy levels in heart and muscle tissue.

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