~ March 2007 - Next-Generation Nutrients for Rapid Relief of Joint Pain
Contents . . .
- Next-Generation Nutrients for Rapid Relief of Joint Pain
By Dale Kiefer
In recent years, adults seeking relief from the crippling pain of arthritis have had to choose between expensive, potentially dangerous pain-relief drugs and safer but slower-acting supplements that support joint health. While supplements such as glucosamine and chondroitin sulfate have been repeatedly shown to improve both arthritis symptoms and joint functionality, it may take weeks or even months for the benefits to be felt, offering little relief in the meantime for those with severe, debilitating joint pain.
Fortunately, several new compounds have been identified that work quickly to relieve pain and promote rapid healing, thus bridging the gap between the onset of discomfort and the beginning of relief. These new-generation compounds not only offer faster-acting pain relief, but also work over time —- either alone or in combination with traditional joint-health supplements -— to provide comprehensive, broad-spectrum support for joint repair and tissue regeneration.
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Fast-Acting Joint Formula . . .
- Stress Reduction Equals Life Extension
By Nicholas Perricone, MD
Reprinted with permission from Dr. Perricone's 7 Secrets to Beauty, Health, and Longevity: The Miracle of Cellular Rejuvenation (Ballantine Books, 2006).
As the mind-body connection has become accepted in mainstream medicine, an entirely new branch of medicine has emerged, known as psychoneuroimmunology. In true holistic fashion, this exciting new area of research brings together knowledge from multiple fields of study in endocrinology, immunology, psychology, neurology, and other fields.
Psychoneuroimmunology integrates the systems of the body and allows us to recognize that cellular rejuvenation can take part on all levels of the mind and body. Perhaps most important, we can learn to control negative emotions and thought processes that upset the delicate balance of health and well-being. Here's how.
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- Uncovering a Hidden Source of Cardiovascular Disease Risk
By William Davis, MD
Anatomy of a portion of the cardiovascular system, showing the heart, aorta, and prominent arteries of the upper torso. An arteriole (small branch of an artery) is shown in cross-section. If you’ve seen a loved one suffer and die from cardiovascular disease, knowing that your own cholesterol is normal can be a relief. Unfortunately, standard cholesterol panels based on fasting blood samples may overlook a hidden, potentially deadly cause of cardiovascular disease: dysfunctional lipid (fat) metabolism patterns known as postprandial disorders.
Postprandial (after-meal) disorders are characterized by abnormally persistent lipid (fat) remnants that persist in the bloodstream for up to 24 hours after eating. Hours after dinner, and even during sleep, these abnormal fat particles can inflict serious damage to your arteries. In fact, postprandial disorders are among the most potent—yet widely ignored—causes of heart disease, stroke, and aneurysm.
In this article, we examine lipid remnants that lurk in the blood between meals, how you can detect the presence of these deadly compounds, and nutritional strategies that can help you reduce and eliminate them.
As you eat a meal of, say, steak, buttered rolls, salad dressing on your lettuce, and cream in your coffee, food passes through your digestive tract. The fats contained within this food are first broken down by enzymes, and then absorbed into veins passing through the liver. From there, they go into the body’s circulatory system.
Four to six hours later, the remnants of your meal should be history. Digestion and clearance from the blood should be quick and efficient. After six hours, these remnants should no longer be detectable in the bloodstream.
In some people, however, meal remnants persist in the blood even 10, 12, or 24 hours later. The longer they stick around, the more opportunity they have to trigger the growth of atherosclerotic plaque in arteries. Clinical studies show that these postprandial lipoproteins (lipids that are transported by protein carriers known as "lipo-proteins") are powerful instigators of coronary plaque, carotid plaque, and aneurysms of the aorta.
These post-meal lipid remnants lurk in the blood from the moment you begin eating, but usually dissipate by the time your "fasting" blood is drawn to assess your risk for vascular disease. Postprandial disorders are therefore almost always overlooked or ignored, and rarely enter into a doctor's assessment and treatment of vascular risk and disease. Although their presence may not be apparent from a fasting blood sample, postprandial lipoproteins can still be a critically important instigator of vascular disease.
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- Growing Evidence Links Resveratrol to Extended Life Span
By Laurie Barclay, MD
The Life Extension Foundation has a 27-year history of introducing cutting-edge therapies for extending life and preventing disease. In 2003, we reported on findings that resveratrol (a substance found in red grapes and other plants) extended the life span of certain cells by as much as 70%.
Since our initial report, resveratrol has continued to demonstrate extraordinary potential in prolonging life. In numerous studies—including those at BioMarker Pharmaceuticals, a Life Extension-sponsored research institution—resveratrol has demonstrated effects that mimic those of caloric restriction, the best-documented anti-aging strategy to date. In all animals in which it has been tested, caloric restriction—the practice of restricting calorie intake while maintaining good nutritional status—improves multiple aspects of age-related decline. Caloric restriction does this, in part, by producing changes in gene expression that are associated with long life and a slowing of the aging process.
Resveratrol is also gaining growing recognition for its promise in fighting age-related diseases ranging from dementia to diabetes. For example, the National Institutes of Health is currently sponsoring a clinical trial investigating resveratrol's ability to fight colon cancer.
In this article, we bring our readers up to date on the latest clinical research on resveratrol, and why leading researchers believe this remarkable nutrient may hold the key to living a longer, more vibrant, disease-free life.
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- Featured Product: Fast-Acting Joint Formula - Life Extension's Fast Acting Joint Formula includes novel joint health nutrients that can be used as a standalone joint health formula or as a complement to other Life Extension bone health formulas such as ArthroMax with FruiteX B.
Designed to help maintain the healthy function of the articular cartilage, the sturdy yet elastic tissue that covers the ends of bones in joints to facilitate smooth movement, Fast Acting Joint Formula contains patented forms of hyaluronic acid and keratin, and a novel plant extract Angelica gigas Nakai.
Hyaluronic acid (HA) is a glycosaminoglycan (similar in many ways to glucosamine and chondroitin) that is widely distributed throughout many connective tissues (cartilage, bones, muscles tendons, ligaments, and skin). It is one of the chief components of the extracellular matrix (such as synovial fluid in joints) and contributes significantly to connective tissue integrity.
Hyaluronic acid serves as one of the primary lubrication components for healthy joint cartilage, where it can help maintain normal joint function by increasing the viscosity of the synovial fluid and by making the cartilage between bones more elastic and smooth-moving. Hyaluronic acid can be delivered directly to the joint space to have a positive biochemical effect on cartilage cells, and is used medically to treat osteoarthritis of the knee.
The hyaluronic acid helps increase production of the joints' synovial fluid.1 Not only is the patented form of keratin (a protein) highly bioavailable, it has one of the highest proportions of the amino acid cysteine, which is involved in sulphur production, an important step in the antioxidant process.2 Herbal extract Angelica gigas Nakai is a novel inhibitor of NF-kappa B activation and has been used in Asia for years as a guard against inflammation.
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