~Kidney Disease

~Kidney Disease
Reprinted with permission of Life Extension®.


For many years, kidney disease has been included in the top ten causes of death by a disease, according to the Centers for Disease Control (CDC). Kidney disease also plays a significant role in hypertension and diabetes, two other diseases that are included in the top ten causes of death in America each year.

The kidneys can be protected from free-radical damage, a major factor in renal health, by supplementing with vitamin E. Vitamin E has been shown to restore tubular flow to rats with severe kidney disease by suppressing the free radicals that cause tubulointerstitial damage.

Tubular disorders such as glomerular impairment may be alleviated by taking taurine, an amino acid shown to protect against experimentally induced lipid peroxidation of the renal glomerular and tubular cells.

Taurine (1000 mg) should be taken 2 to 3 times a day.

Homocysteine can be very damaging to kidneys. Dialysis patients often require high levels of homocysteine-lowering nutrients such as folic acid, vitamin B12, TMG (also known as betaine or trimethylglycine), and vitamin B6. Folic acid was used in an important study conducted on 82 patients undergoing dialysis (70 used hemodialysis and 12 used peritoneal dialysis) 3 times a week for 4 weeks. The results showed that both groups had homocysteine concentration reduced by 35% after taking 2.5 to 5 mg folic acid after each dialysis treatment.

Although dialysis had the effect of lowering homocysteine levels, folic acid further reduced homocysteine levels and, more importantly, had long-term effects even after folic acid supplementation was withdrawn. "Homocysteine concentrations remained decreased in 20 patients four weeks after withdrawal of folic acid supplementation."

The established dosages for these critical nutrients are as follows:

Folic acid (800 mcg)

TMG, or betaine, (500 mg ) taken twice each day

Vitamin B12 (300 mcg)

Vitamin B6 (150 mg minimum) taken throughout the day

If you have any questions, please contact us at info@lifeextensionvitamins.com or 1-888-771-3905.


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