~ Enzyme Discovery Could Lead to Life-Extending Drugs

U.S. researchers have discovered a way of increasing the activity of potent anti-aging enzymes called sirtuins. David Sinclair of Harvard Medical School and colleagues found several biologically active compounds that can more than double sirtuin activity.

One of these compounds was resveratrol, the antioxidant that is largely responsible for the health benefits of red wine. When the scientists added some of these compounds to yeast cells growing in culture, the cells produced 70% more daughter cells than normal - the production of daughter cells is a reliable indicator of yeast's youthfulness.

Tests on human cells also produced promising results. Those treated with sirtuin boosters lived long lives in the lab, even after exposure to DNA-damaging ionizing radiation, which normally shortens the lifespan of a cell. Furthermore, preliminary results of ongoing experiments suggest that these compounds can extend the lifespan of a nematode worm known as C. elegans, and the fruit fly.

Sinclair says that his findings suggest that sirtuins "serve as guardians of the cell" and "allow cells to survive damage and delay cell death." Sinclair's work adds further support to the increasingly popular theory that sirtuins control aging in virtually all living organisms. Therefore, it may be that sirtuin boosters will provide us with a potent class of anti-aging drugs, and possibly the much longed for fountain of youth.

SOURCE/REFERENCE: Reported by www.washingtonpost.com on the 25th August 2003.

Free Shipping in the Continental U.S. on Orders over $50
The statements made here have not been evaluated by the FDA. The foregoing statements are based upon sound and reliable studies, and are meant for informational purposes. Consult with your medical practitioner to determine the underlying cause of your symptoms. Please always check your purchase for possible allergins and correct dosage on the bottle before use.

While we work to ensure that product information is correct, on occasion manufacturers may alter their ingredient lists. Actual product packaging and materials may contain more and/or different information than that shown on our Web site. We recommend that you do not solely rely on the information presented and that you always read labels, warnings, and directions before using or consuming a product. For additional information about a product, please contact the manufacturer. Content on this site is for reference purposes and is not intended to substitute for advice given by a physician, pharmacist, or other licensed health-care professional. You should not use this information as self-diagnosis or for treating a health problem or disease. Contact your health-care provider immediately if you suspect that you have a medical problem. Information and statements regarding dietary supplements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent any disease or health condition. Life Ex Online assumes no liability for inaccuracies or misstatements about products.