~ April 2008 - Why Aging People Become Depressed, Fatigued, and Overweight

Contents . . .
  • Why Aging People Become Depressed, Fatigued, and Overweight

    By William Faloon

    Serotonin is a compound in the brain that promotes feelings of personal security, relaxation, and confidence. A serotonin deficiency can result in sleep disturbance, anxiety, depression, and a propensity to overeat, particularly carbohydrates like simple sugars.

    Startling research reveals that serotonin levels decline as we age!1-3 These findings provide a biochemical rationale to explain common age-related disorders such as depressed mood and sleep difficulties. Based on these discoveries, aging people may appreciably improve their health by restoring serotonin to youthful levels.

    The amino acid tryptophan is needed to produce serotonin in the brain.4 While the amount of tryptophan in a typical diet meets basic metabolic requirements, it often fails to provide optimal brain serotonin levels.

    Ever since the FDA restricted the importation of tryptophan for use in dietary supplements, there has been an upsurge in the percentage of overweight and obese Americans.

    One could argue that a widespread serotonin deficiency is at least partially responsible for the record numbers of depressed, sleep-deprived, and overweight individuals.

    Read more . . .
  • Guard Your Precious Proteins Against Premature Aging

    By Steven Joyal, MD

    It may seem inconceivable, but scientists long ago learned why aging people suffer so many disorders related to their eyes, kidneys, brain, and vascular system.

    While these pathological processes are accelerated in diabetics, they affect all aging people to one degree or another.

    In a startling revelation, Steven Joyal, MD, lays out an innovative, but remarkably simple program to enable both diabetics and normal aging humans to avoid these horrendous biological consequences.

    The article you are about to read is a summary of Dr. Joyal's new book titled What Your Doctor May Not Tell You About Diabetes.

    In fact, this book contains vital information for every aging person. The reason is that most aging people suffer pre-diabetic pathologies and should therefore follow similar strategies to protect against common age-related diseases.

    Read more . . .
  • Protecting Against Glycation and High Blood Sugar with Benfotiamine

    By Julius G. Goepp, MD

    For decades, European doctors have prescribed diabetic patients a fat-soluble form of vitamin B1 called benfotiamine to treat neuropathies and help prevent complications such as blindness, kidney failure, heart attack, and limb amputation.

    Benfotiamine blocks destructive biochemical pathways that enable high blood sugar levels to damage nerves and small blood vessels.

    Benfotiamine also inhibits the formation of advanced glycation end products in both diabetic and normal aging organisms. Glycation not only causes kidney, nerve, and retinal damage in diabetics, but is also a significant contributory factor in cardiovascular disease and other aging disorders in adults without diabetes.1-6

    Here, we'll explore how to use benfotiamine to help protect against the dangers of elevated blood sugar and toxic glycation reactions.

    Read more . . .
  • Aging and Glycation

    Steven V. Joyal, MD

    Physicians and patients alike are beginning to realize that there is a valuable blood test that can help assess the level of glycation, a process implicated in accelerated aging.

    The hemoglobin A1c test is a well known tool for following long-term glucose control in patients with diabetes. However, the same blood test also helps identify age-accelerating glycation reactions in the body. The hemoglobin A1c blood test is thus useful in non-diabetics who want to guard against this destructive glycation process.Here, we’ll examine the importance of making sure your hemoglobin A1c is in a safe range and what to do if it is not.

    Read more . . .
  • Newly Discovered Health Benefits of Vitamin C

    By Julius Goepp, MD

    Vitamin C is rapidly finding new applications in protecting against endothelial dysfunction, high blood pressure, and the blood vessel changes that precede heart disease.1-3 Additional research is discovering that vitamin C can be helpful in preventing asthma,4 protecting against cancer,5 and supporting healthy blood sugar levels in diabetics.6

    While often taken for granted, vitamin C is a critical supplement in your program to improve cardiac health and avoid degenerative diseases.

    Read more . . .
  • New Research on the Health Benefits of Green Tea

    By Julius Goepp, MD

    In laboratories around the globe, green tea is sparking tremendous excitement as new health applications keep being discovered.

    The most active green tea constituent is called epigallocatechin gallate. This unique flavonoid favorably alters pathways underlying pathological processes such as cancer,1-4 cardiovascular disease,5,6 diabetes,7 obesity,8 and Alzheimer's and Parkinson's diseases.9-11 All of this points to green tea as a broad-spectrum nutrient that may promote long life.4,12

    Green tea is consumed routinely in Asian populations, who have greater longevity and lower mortality rates for diseases that are prevalent in Western society.

    Given the huge scientific literature supporting the positive role of green tea in preventing neurodegenerative diseases, not to mention its benefits in helping to prevent cancer and other diseases, as well as its lack of toxicity, there isample reason for consuming green tea poly-phenols on a regular basis.

    In this article, we have interviewed international scientists on their current research into the myriad life-extending and life-enhancing benefits of green tea.

    Read more . . .
  • Featured Product: TryptoPure Plus - TryptoPure L-Tryptopha is suitable for vegetarians, additive-free, solvent-free, 100% fermented, and GMP certified.

    L-Tryptophan is an essential amino acid, which means it cannot be synthesized by the human body and therefore must be part of the diet or supplementation. The best sources for tryptophan are high protein foods such as oats, bananas, dried dates, dairy products, fish, many nuts, and poultry.

    Tryptophan is critical in helping your body produce proteins for muscle, hair, and skin. Unfortunately tryptophan is the least abundant amino acid in your diet. Even a person on a high protein diet gets less than 1.5 grams of tryptophan a day. What's more, when you ingest tryptophan it undergoes a process that dramatically reduces the amount actually absorbed. Some experts estimate that only 1% of the dietary tryptophan you take in reaches the brain. For some this is sufficient, but for others, low levels can adversely affect sleep, weight, and mood.

    Tryptophan is a precursor for serotonin. Unlike other products that indirectly influence serotonin production or increase metabolism, L-tryptophan is a direct precursor that results in almost immediate increases in circulating serotonin, which is one of the primary neurohormones involved with sleep and mood.

    In those people with low serotonin levels, L-tryptophan has been shown to help establish and maintain healthy levels, which may help to improve mood1 and reduce tension. In those people with serotonin levels already within the normal range, L-tryptophan acts as a natural sleep aid, not only helping people fall asleep, but also helping them stay asleep throughout the night and wake without grogginess. For this reason, some experts believe tryptophan can be a safe and effective sleep aid when added to your diet as a supplement. Supplementing your diet with tryptophan, specifically TryptoPure, may mean a more restful night's sleep, a brighter, mood and a host of other benefits.

    Until recently, Ajinomoto only sold their TryptoPure brand tryptophan for medical use through doctors, hospitals and other professional health care facilities. It is the only tryptophan to have an FDA-approved Drug Master File. That means it's pure enough to be used as an active pharmaceutical ingredient in pharmaceutical products.

    Life Extension has selected TryptoPure as its tryptophan of choice. TryptoPure is the most trusted tryptophan available today. TryptoPure is suitable for vegetarians, additive-free, solvent-free, 100% fermented, and GMP certified.

    Supplement Facts

    Serving Size: 1 vegetarian capsule

    Servings Per Container: 90

    Amount Per Serving
    • TryptoPure L-Tryptophan (100% pure USP pharmaceutical-grade L-tryptophan) - 500mg
    Other ingredients: vegetable cellulose (capsule).

    This product contains NO milk, egg, fish, peanuts, crustacean shellfish (lobster, crab, shrimp), soybeans, tree nuts, wheat, yeast, gluten, corn, or rice. Contains NO sugar, and no artificial sweeteners, flavors, colors, or preservatives.

    TryptoPure™ is a trademark of Ajinomoto Company, Inc.

    Dosage and Use:

    Take one capsule 1-3 times daily or as recommended by a healthcare practitioner. For maximum absorption, take with 6-8 oz. of water or a small amount of carbohydrate such as diluted juice. Take separately from food or supplements containing protein or amino acids.

    Vitamin B6 is an essential cofactor in the conversion of L-tryptophan to serotonin in the body, while niacinamide plays an important role in enabling the body to properly utilize amino acids like tryptophan. Therefore, those taking L-tryptophan may find optimal results by consuming a B-complex supplement during the day that provides at least 50 mg of niacinamide and 50 mg of vitamin B6.

    Caution: Serotonin syndrome is characterized by high levels of serotonin and symptoms like confusion, sweating, agitation, nausea, involuntary muscle contractions, and racing heartbeat. Do not take L-tryptophan if you experience these symptoms. Do not take L-tryptophan in combination with other agents that increase serotonin levels in the central nervous system. Agents that increase serotonin levels can induce psychiatric medications (e.g. antidepressants, lithium), migraine medications (e.g. sumatriptan), Parkinson's disease medications (e.g. carbidopa), and dextromethorphan, an over-the-counter cough suppressant.
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