~ Aging Stem Cells Linked to Leukemia in Elderly

HealthDay, 06-22-05

TUESDAY, June 21 (HealthDay News) -- Aging stem cells may be behind an increased risk of infection and leukemia in older people, according to a Stanford University School of Medicine study.

The report appears in this week's issue of the Proceedings of the National Academy of Sciences.

The Stanford team found that in older mice, bone marrow stem cells that create new blood cells produce fewer immune cells. That means the bodies of older mice are less able to fight infection.

As well as producing fewer immune cells, the aging blood-forming stem cells use genes known to be involved in leukemia -- cancers that affect blood cells. This may be one reason why older people have an increased risk of developing certain kinds of leukemia, the study authors said.

The findings provide more evidence that aging stem cells or stem cells responding to conditions in an aging body may be the source of a number of age-related health problems.

"Aging results in a diminished capacity of the body to maintain tissue and organ function. Since we know the cells mediating this maintenance are stem cells, it doesn't take a great leap of faith to think that stem cells are at the heart of that failure," study co-author and postdoctoral scholar Derrick Rossi said in a prepared statement.

The researchers said this finding could lead to ways to improve immune function or prevent leukemia in older people.

More information

The Alliance for Aging Research has more about aging.

For the latest health news & Health-Life Services like tools, calculators, & a physician locator, go to www.healthday.com.


Free Shipping in the Continental U.S. on Orders over $50
The statements made here have not been evaluated by the FDA. The foregoing statements are based upon sound and reliable studies, and are meant for informational purposes. Consult with your medical practitioner to determine the underlying cause of your symptoms. Please always check your purchase for possible allergins and correct dosage on the bottle before use.

While we work to ensure that product information is correct, on occasion manufacturers may alter their ingredient lists. Actual product packaging and materials may contain more and/or different information than that shown on our Web site. We recommend that you do not solely rely on the information presented and that you always read labels, warnings, and directions before using or consuming a product. For additional information about a product, please contact the manufacturer. Content on this site is for reference purposes and is not intended to substitute for advice given by a physician, pharmacist, or other licensed health-care professional. You should not use this information as self-diagnosis or for treating a health problem or disease. Contact your health-care provider immediately if you suspect that you have a medical problem. Information and statements regarding dietary supplements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent any disease or health condition. Life Ex Online assumes no liability for inaccuracies or misstatements about products.