~ 062410 Study: Folate May Aid Spinal Cord Healing

United Press International

A U.S. National Institutes of Health-funded laboratory study suggests the B vitamin folate can promote healing in damaged rat spinal cord tissue.

The investigation, led by University of Wisconsin-Madison Dr. Bermans Iskandar, an associate professor of neurosurgery, showed the nerve regeneration in the rats was triggered by a change in DNA.

The researchers said the healing effects of the vitamin increased with the dosage, until regrowth of the damaged tissue reached a maximum level, after which it declined progressively with increasing doses until it reached the level seen in the absence of the vitamin.

The scientists said they discovered folate stimulated a process known as DNA methylation -- a biochemical process in which chemical compounds known as methyl groups are attached to DNA.

"The ability to change gene function through DNA methylation suggests exciting new prospects for understanding the origins of disease and for developing new treatments," Iskandar said. "Our study showed that folate, a commonly available dietary supplement known to change gene functioning, did so in a way that fosters nervous system repair."

Folate occurs naturally in leafy green vegetables and other foods. The synthetic form, folic acid, is used to supplement cereal grains in the United States. The NIH said the vitamin is important for the formation of the brain and spinal cord in the early embryo.

The research is reported in the Journal of Clinical Investigation.

Copyright United Press International 2010

Related Products and Information

Free Shipping in the Continental U.S. on Orders over $50
The statements made here have not been evaluated by the FDA. The foregoing statements are based upon sound and reliable studies, and are meant for informational purposes. Consult with your medical practitioner to determine the underlying cause of your symptoms. Please always check your purchase for possible allergins and correct dosage on the bottle before use.

While we work to ensure that product information is correct, on occasion manufacturers may alter their ingredient lists. Actual product packaging and materials may contain more and/or different information than that shown on our Web site. We recommend that you do not solely rely on the information presented and that you always read labels, warnings, and directions before using or consuming a product. For additional information about a product, please contact the manufacturer. Content on this site is for reference purposes and is not intended to substitute for advice given by a physician, pharmacist, or other licensed health-care professional. You should not use this information as self-diagnosis or for treating a health problem or disease. Contact your health-care provider immediately if you suspect that you have a medical problem. Information and statements regarding dietary supplements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent any disease or health condition. Life Ex Online assumes no liability for inaccuracies or misstatements about products.