Most animals, fish, reptiles and birds make their own vitamin C. We don't make our own vitamin C. If we did we would have less heart disease, hypertension, gallbladder disease, cancer, allergies, asthma, osteoporosis, Alzheimer's, Parkinson's, PTSD, sleep disorders, depression, anxiety disorders, chronic fatigue and chronic pain, among other things.
I know this because in each of these diseases clinical studies show lower levels of TISSUE ascorbate, not serum, but TISSUE.
The distinction is important. Clinical studies cannot tell you tissue levels unless your subjects are killed and slices of a particular body part are tested for vitamin C. So we use animals OR we test the tissues of persons who have died and we know had a certain disease or condition.
200 mg of daily vitamin C will keep you from having scurvy, BUT will never restore OR maintain tissue levels of C. The amount of C needed? Well, you are currently helping to determine that. It may be as low as 1,000 mg twice a day every day (of regular C not liposomal) or it may be 10,000 mg. That is to maintain tissue levels (again, not serum). That dose will not normalize or restore tissue (brain, pituitary, thyroid, adrenals, eyes, lungs, saliva, ovaries, testes, heart, arteries, bone, joints, ligaments, tendons, etc.) levels of ascorbate (vitamin C).
In Dec 2010 researchers in New Zealand found that the amount of C needed to optimize serum (blood) levels of ascorbate in especially bred GLO minus mice (mice unable to make their own C, just as humans can't) had NO effect on tissue levels. They aren't the first to discover this as many studies trying to treat varying conditions found they could not restore ascorbate tissue levels with oral vitamin C. They could do so using intravenous vitamin C. What the New Zealand researchers also found was that doses of vitamin C 5 times that used to maintain optimal serum levels, taken over 24 hours, began to restore tissue levels. The key to replenishing tissues was divided high doses of vitamin C so that the serum consistently maintained elevated levels of C which then began to distribute itself into tissue body stores.
The researchers compared the GLO mice (genetically engineered to lack the ability to make their own C like humans) to wild type, vitamin C producing mice. At all points, even with supplementation the GLO mice could not reach levels of C found naturally in the wild type mice, Wild type mice all had higher tissue levels of C under all conditions. We really are genetically challenged.
We need more C and we need to take vitamin C at least twice a day, never just once a day. Liposomal C is more absorbable within cells than any other type of vitamin C including intravenous. To restore tissue levels likely takes 4-8 weeks IF no infection or injury is currently present. If infection or injury is present PLEASE call for guidance. Otherwise 2,000-3,000 mg of liposomal C taken twice a day for 4-8 weeks (total 4,000-6,000 mg liposomal) should 'fill you up'. At that point, which you will recognize because you have a sense of well-being and natural energy, quality sleep, and a generous mood, you may need to reduce your dose. Unlike non-liposomal C you can take too much. Symptoms will actually be a return of symptoms you thought were going or gone.
As we are learning together you have to know your dose, be both consistent and persistent, and understand that in animals vitamin C levels vary day to day and hour to hour. Maintenance is likely 1,000 mg liposomal C twice a day but that won't be enough to 'fill up' when you first begin and if infection or injury occur you may need as much as 3,000 mg liposomal three or four times a day for a few days or even weeks to repair or fight infection and maintain tissue stores. Life is dynamic and your C intake needs to support real world conditions. We will all learn to do this over time.
Though hard to believe 1,000 mg liposomal C will give serum values equivalent to 4,000-5,000 mg of regular C. You don't need more or less you need how much you need, hour by hour and day by day and make sure you get it.
KEEP RECORDS of what day it is in your building program, your dose, mood, energy, sleep, inflammation (if present) and/or any other symptoms. Check in. Most of all get to your place of healing and regeneration. Vitamin C makes your parts come together in new, better ways. If there was ever a longevity secret vitamin C is it. I have begun thinking of vitamin C as biochemical forgiveness.