~ Vinpocetine: A Powerful Memory Enhancer
Vinpocetine is a powerful memory enhancer.
It facilitates cerebral metabolism by improving cerebral microcirculation (blood flow), stepping up brain cell ATP production (ATP Is the cellular energy molecule), and utilization of glucose and oxygen.
What all this means is that vinpocetine has a lot of the effects of several other cognitive enhancers all put together. Vinpocetine is shown to compare favorably to placebo, vincamine, papaverine, DHT (Hydergine), xanthinol nicotinate, meclophenoxate, cinnarizine, niacin, cyclandelate, difenidol, and ifenprodil.
Vinpocetine is often used for the treatment of cerebral circulatory disorders such as memory problems, acute stroke, aphasia (loss of the power of expression), apraxia (inability to coordinate movements), motor disorders, dizziness and other cerebro-vestibular (inner-ear) problems, and headache. Vinpocetine Is also used to treat acute or chronic ophthalmological diseases of various origin, with visual acuity improving in 70% of the subjects. Vinpocetine also is used In the treatment of sensor/neural hearing impairment.
Hundreds of studies on vinpocetine have been done, often comparing its effects to other cognitive enhancers. The incidence of side effects in humans using the drug orally is usually less than 1% of a study's participants, with the unwanted effects disappearing with discontinued use. One series of studies Involved 882 patients with neurological disorders ranging from stroke to cerebral Insufficiency. Significant Improvements were found In 62% of the patients.
In one of the study, cerebral insufficiency patients were asked to memorize a list of 10 words. Without vinpocetine the subjects were able to memorize an average of 6 words. After a month of treatment the average went up to 10 words. Vinpocetine Is the only drug that improves cerebral metabolism (glucose and oxygen metabolism, hypoxia (deficient blood oxygenation) tolerance, increased ATP concentration, and increased norepinephrine and serotonin turnover), cerebral microcirculation, and selectively increases blood flow to the brain (improving blood flow to the impaired area without lowering blood flow to other parts of the body).
As if the medical uses of vinpocetine were not amazing enough, in one double-blind crossover study, normal, healthy volunteers showed incredible short term memory Improvement an hour after taking 40 mg of vinpocetine. The volunteers took a computer-administered short term memory test called a Sternberg Memory Scanning Test.
The volunteers (all women between the ages of 25 and 40) were shown one to three digits on a computer screen, then a moment later were shown a long string of digits. The volunteers then Indicated whether any of the first digits appeared In the second long string. The time the volunteer took to remember was then assessed. On a placebo the women took an average of 700 milliseconds to respond when the first set contained 3 digits. With vinpocetine they averaged under 450 milliseconds!
Vinpocetine Is a derivative of vincamine (which Is an extract of the periwinkle). Although they have many similar effects vinpocetine has more benefits and fewer adverse effects than vincamine.
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