~ Jul 07 Testosterone's Overlooked Role in the Treatment of Diabetes in Men - References

References

1. Moller J. Cholesterol: Interactions with Testosterone and Cortisol in Cardiovascular Diseases. Berlin: Springer-Verlag; 1987.

2. Ding EL, Song Y, Malik VS, Liu S. Sex differences of exogenous sex hormones and risk of type II diabetes.

JAMA. 2006 Mar 15;295(11): 1288-99.

3. Tibblin G, Adlerberth A, Lindstedt G, Bjorntorp P. The pituitary-gonadal axis and health in elderly men: a study of men born in 1913. Diabetes. 1996 Nov;45(11):1605-9.

4. Barud W, Piotrowska-Swirszcz A, Ostrowski S, Palusinski R, Makaruk B. Association of obesity and insulin resistance with serum testosterone, sex hormone binding globulin and estradiol in older males. Pol Merkur Lekarski. 2005 Nov;19(113):634-7.

5. Bergamini E. Different mechanisms in testosterone action on glycogen metabolism in rat perineal and skeletal muscles. Endocrinology. 1975 Jan;96(1):77-84.

6. Hayward RA, Manning WG, Kaplan SH, Wagner EH, Greenfield S. Starting insulin therapy in patients with type 2 diabetes: effectiveness, complications, and resource utilization. JAMA. 1997 Nov 26;278(20):1663-9.

7. Kapoor D, Goodwin E, Channer KS, Jones TH. Testosterone replacement therapy improves insulin resistance, glycaemic control, visceral adiposity and hypercholesterolaemia in hypogonadal men with type 2 diabetes.

Eur J Endocrinol. 2006 Jun;154(6):899-906.

8. Gascon A, Belvis JJ, Berisa F, Iglesias E, Estopinan V, Teruel JL. Nandrolone decanoate is a good alternative for the treatment of anemia in elderly male patients on hemodialysis. Geriatr Nephrol Urol. 1999;9(2):67-72.

9. Morgentaler A, Rhoden EL. Prevalence of prostate cancer among hypogonadal men with prostate-specific antigen levels of 4.0 ng/mL or less. Urology. 2006 Dec;68(6):1263-7.

10. No authors listed. Type 2 diabetes in children and adolescents. American Diabetes Association. Diabetes Care. 2000 Mar;23(3):381-9.























TABLE 1. Testosterone Improves Blood Sugar, HbA1c in “Anthony,” a 50-Year-Old Diabetic
Date 24-hour
Long-acting
insulin use
Glucose
(mg/dL)
HbA1c
(%)
Testosterone
(ng/dL)
Sex Hormone-
Binding Globulin
(nmol/mL)
Treatment: weekly
testosterone
injections
7/18/0614 units 488 >18 643 38 2
7/29/06 30 units141 15.7 2
8/06/06 40 units 154 15.2 1.5
8/12/06 50 units 13.5 953 1
8/28/06 60 units 161 11.8 493 1
9/02/0670 units 165 11.2 522 1
9/15/06 75 units 10.1 1
9/22/06 80 units 308 9.5 894 1
10/28/06 75 units 47 8.3 1
11/14/06 75 units 135 7.9 297 1
12/18/06 88 units175 7.7 1.5
1/27/07 100 units 65 7.4792 1.5


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