SAMe (S-adenosyl-methionine) is an amino acid derivative normally synthesized in the body that is excellent for muscle pain, fibromyalgia, joint pain, rheumatoid arthritis, depression and liver disease. Source: Life Extension Foundation Ingredients: SAMe Sale Price: $39.99 Take advantage of FREE air shipping in the USA! Read More . . . NEW QUANTITY - NEW PRICE! Imported from Europe: enteric coated. Beware of cheap nonenteric coated brands that are not stabilized. About SAMe SAM is a natural form of bioactive methionine, sold as an antidepressant drug in Europe. SAMe results from the conversion of methionine by ATP and SAMe synthetase. SAMe is a "methyl donor" - it contributes a methyl group to help other molecules become active. SAMe is utilized by the body in three important pathways: Methylation (contributing methyl groups) The synthesis of polyamines (for cell growth, gene expression, neuron regeneration, etc.) Transsulphuration (synthesis of cysteine, glutathione and other sulfate groups.) Conditions: Age-Associated Mental Impairment (Brain Aging) Alcohol-Induced Hangover Depression Fibromyalgia Liver (CIRRHOSIS) Muscular Dystrophy NOTE: TMG is recommended to enhance SAMe levels and neutralize bad homocysteine levels that increase with supplementation with SAMe. To learn more about SAMe and TMG, please click here. How to Order To order online, click on the "Order" box below. To see a list of all supplements, please check our Index or use our Search feature. If you have any questions, please contact us at info@lifeextensionvitamins.com, 1-510-527-3005 or 1-888-771-3905. samRetail Price: $78.00Sale Price: $39.99 50: tablets/200mg.ea Related links - TMG Click for more information. FREE AIR MAIL SHIPPING IN THE UNITED STATES! The statements made here have not been evaluated by the FDA. The foregoing statements are based upon sound and reliable studies, and are meant for informational purposes. Consult with your medical practitioner to determine the underlying cause of your symptoms. Copyright 1997-2010 Life Extension Vitamin Supplies and Life Extension Institute, Inc. All rights reserved.